Publications

View additional publications by this faculty member.

2022-2021

Eisenhoffer, G.T., Clouthier, D., Cox, T., Saint-Jeannet, J.P., Taneyhill, L.A., Trainor, P.A. and Moody, S.A. (2020) The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting. Amer. J. Med. Genetics, Part A. 182: 1555-1561. doi 10.1002/ajmg.a.61602

Brugmann, S., Clouthier, D.E., Saint-Jeannet, J.P., Taneyhill, L.A., and Moody, S.A. (2021) The Society for Craniofacial Genetics and Developmental Biology 43rd Annual Meeting. Amer. J. Med. Genetics, Part A. 185: 1932-1939. doi: 10.1002/ajmg.a.62150.

Moody, S.A. (2021) Xenopus explants and transplants. Cold Spring Harbor Protocols, doi 10:1101/pdb.top097337.

Leibovich, A., Moody, S.A., Klein, S.L. and A. Fainsod (2022) Xenopus: a Model to Study Natural Genetic Variation and its Disease Implications. In: “Xenopus, from basic biology to disease models in the genomic era” CRC Press. Boca Raton. pp 313-324.

Onjiko, R.M., Nemes, P., and S.A. Moody (2021) Altering metabolite distribution at Xenopus cleavage stages affects left-right gene expression asymmetries. genesis, The Journal of Genetics and Development, 59: e23418. doi : 10.1002/dvg.23418. PMID: 33826226.

Mehdizadeh, T., Majumdar, H.D., Ahsan, S., Tavares, A.L.P. and S.A. Moody (2021) Mutations in SIX1 associated with Branchio-oto-renal Syndrome (BOR) differentially affect otic expression of putative target genes. J. Developmental Biology 9: 25. doi: 10.3390/jdb9030025. PMID: 34208995.

Tavares, A.L.P., Jourdeuil, K., Neilson, K.M., Majumdar, H.D. and S.A. Moody (2021) Sobp modulates Six1 transcriptional activation and is required during craniofacial development. Development 148: dev199684 doi: 10.1242/dev.199684 PMID: 34414417.

Coppenrath, K., Tavares, A.L.P., Shaidani, N-I., Wlizla, M., Moody, S.A., and M. Horb (2021) Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease. genesis, The Journal of Genetics and Development doi: 10.1002/DVG.23453. PMID: 34664392

Karpinski, B.A., Maynard, T.M., Bryan, C.A., Yitsege, G., Horvath, A., Lee, N.H., Moody, S.A., and A.S. LaMantia (2022) Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 Deletion Syndrome. Disease Models & Mechanisms 15: dmm 047357. doi: 10.1242/dmm.047357. PMID: 33722956.

Klein, S.L., Tavares, A.L.P., Peterson, M., Sullivan, C.H., and S.A. Moody (2022) Repressive interactions between transcription factors separate different ectodermal domains. Frontiers in Cell and Developmental Biology 10: 786052. doi: 10.3389/fcell.2022.786052

Gur, M., Edri, T., Moody, S.A. and A. Fainsod (2022) Retinoic acid is required for normal morphogenetic movements during gastrulation. Frontiers in Cell and Developmental Biology 10: 857230. doi: 10.3389/fcell.2022.857230.

2020 - 2017

Maynard, T.M., Zohn, I.E., Moody, S.A. and LaMantia, A.S. (2020) Suckling, Feeding and Swallowing: Behaviors, Circuits and Targets for Neurodevelopmental Pathology. Ann. Rev. Neuroscience 43: 315-336. PMID: 32101484.

Eisenhoffer, G.T., Clouthier, D., Cox, T., Saint-Jeannet, J.P., Taneyhill, L.A., Trainor, P.A. and Moody, S.A. (2020) The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting. Amer. J. Med. Genetics, Part A. 187: 1555-1561. doi 10.1002/ajmg.a.61602

Shah, A.M., Krohn, P., Baxi, A.P., Tavares, A.L.P., Sullivan, C.H., Chillakuru Y.R., Majumdar, H.D., Neilson, K.M., and S.A. Moody (2020) Six1 proteins with human Branchio-oto-renal mutations differentially affect cranial gene expression and otic development. Disease Models & Mechanisms 13: dmm043489. doi: 10.1242/dmm.043489. PMID: 31980437.

Maynard, T.M., Horvath A., Bernout, J., Karpinski, B., Tavares A.L.P., Zheng, Q., Spurr, L., Olender, J., Moody, S.A., Fraser, C.M., A.S. LaMantia, and N.H. Lee (2020) Transcriptional dysregulation in developing trigeminal sensory neurons in the LgDel mouse model of DiGeorge 22q11.2 deletion syndrome. Human Molecular Genetics 29: 1002-1017. doi: 10.1093/hmg/ddaa024. PMID: 32047912.

Leibovich, A. Edri, T., Klein, S.L., Moody, S.A. and A. Fainsod (2020) Natural variation among embryos leads to corresponding scaling in gene expression. Developmental Biology 462: 165-179. doi: 10.1016/j.ydbio.2020.03.014. PMID: 32259520.

Moody, S.A. and S.L. Klein (2019) Deferred-use molecules and decision-making in development. In: Deferring development: Setting aside cells for future use in development and evolution. C. Bishop and B. K. Hall Eds., CRC Press, pp 29-52.

Moody, S.A. (2019) Cleavage blastomere deletion and transplantation. Cold Spring Harbor Protocols doi: 10.1101/pdb.prot097311. PMID: 29769398.

Moody, S.A. (2019) Cleavage blastomere explant culture. Cold Spring Harbor Protocols doi: 10.1101/pdb.prot097303. PMID: 29769392.

Moody, S.A. (2019) Analysis of Cell Fate Commitment in Xenopus Embryos. Cold Spring Harbor Protocols doi: 10.1101/pdb.top097246. PMID: 29769394.

Motahari, Z., Moody, S.A., Maynard, T.M., LaMantia, A.S. (2019) In the Line-up: Deleted genes associated with DiGeorge/22q11.2 Deletion Syndrome: Are they all suspects? J. Neurodevel. Disorders 11:7 doi: 10.1186/s11689-019-9267-z. PMID:31174463.

Sullivan, C.H., Majumdar, H.D., Neilson, K.M., and S.A. Moody (2019) Six1 and Irx1 have reciprocal interactions during cranial placode and otic vesicle formation. Developmental Biology 446: 68-79. doi: 10.1016/j.ydbio.2018.12.003. PMID: 30529252.

Lombard-Banek, C., Moody, S.A., Manzini, M.C., and P. Nemes (2019) Microsampling capillary electrophoresis mass spectrometry enables single-cell proteomics in complex tissues: Developing cell clones in live Xenopus laevis and zebrafish embryos. Analytical Chemistry 91: 4797-4805. doi: 10.1021/acs.analchem.9b00345. PMID: 30827088.

Taneyhill, L.A., Moody, S.A., Cox, T., Klein, O., Marcucio, R., Schneider, R. and Trainor, P.A. (2019) The Society for Craniofacial Genetics and Developmental Biology 41st Annual Meeting. Amer. J. Med. Genetics, Part A. 179: 864-869. doi: 10.1002/ajmg.a.61090. PMID: 30793834

Baxi, A., Lombard-Banek, C., Moody, S.A., and P. Nemes (2018) Proteomic characterization of the neural ectoderm fated cell clones in the Xenopus laevis embryo by high-resolution mass spectrometry. ACS Chemical Neuroscience 9: 2064-2073. doi: 10.1021/acschemneuro.7b00525. PMID: 29578674.

Moody, S.A. (2018) Lineage tracing and fate mapping. Cold Spring Harbor Protocols doi: 10.1101/pdb.prot097253. PMID: 29769388.

Moody, S.A. (2018) Microinjection of mRNAs and oligonucleotides. Cold Spring Harbor Protocols doi: 10.1101/pdb.prot097261. PMID: 29769401.

Gammill, L., Cox, T., Moody, S., Taneyhill, L., Trainor, P., and Marcucio, R. (2018) The Society for Craniofacial Genetics and Developmental Biology 40th annual meeting. Amer. J. Med. Genet. Part A, 176: 1270-1273. doi: 10.1002/ajmg.a.38653. PMID: 29681098.

Moody, S.A. (2018) Case study 14: Illmensee and Mahowald, 1974, Pole plasm. In: Ahead of the Curve: Hidden Breakthroughs in the Biosciences. Volume 2. D.S. Adams and M. Levin Eds., Bristol, UK, Institute of Physics Publishing, pp.4-1 to 4-3.

Sater, A.K. and S.A. Moody (2017) Using Xenopus to understand human disease and developmental disorders. genesis, The Journal of Genetics and Development 55. doi: 10.1002/dvg.22997. PMID: 28095616.

Neilson, K.M., Abbruzzesse, G., Kenyon, K.L., Bartolo, V., Krohn, P., Alfandari, D., and S.A. Moody (2017) Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development. Developmental Biology 421: 171-182. PMID: 27940157

Onjiko, R., Plotnick, D.O., Moody, S.A., and P. Nemes (2017) Metabolic comparison of dorsal versus ventral cells directly in the live 8-cell frog embryo by microprobe single-cell CE-ESI-MS. Analytical Methods 9: 4964-4970. PMID: 29062391.

Onjiko, R.M., Potero, E.P., Moody, S.A. and P. Nemes (2017) Microprobe capillary electrophoresis mass spectrometry for single-cell metabolomics in live frog (Xenopus laevis) embryos. J. Vis. Experiments 130: e56956, doi:10.3791/56956. PMID:29286491.

Sherman, J.H., Karpinski, B., Fralish, M., Cappuzzo, J., Dhindsa, D., Thal, A. Moody, S.A., LaMantia, A.S., and T.M. Maynard (2017) Foxd4 is essential for establishing neural cell fate and for neuronal differentiation. genesis, The Journal of Genetics and Development 55: ePub. doi: 10.1002/dvg.23031. PMID: 28316121 (Cover article)

Onjiko, R., Portero, E., Moody, S.A., and P. Nemes (2017) In situ microprobe capillary electrophoresis mass spectrometry: metabolic reorganization in single differentiating cells in the live vertebrate (X. laevis) embryo. Analytical Chemistry 89: 7069-7076. PMID: 28434226 (Cover article)

Marchak, A., Grant, P., Neilson, K.M., Majumdar, H.D., Yaklichkin, S., Johnson, D., and S.A. Moody (2017). Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates. Developmental Biology 429: 213-224. PMID: 28663133.

2016 - 2013

Klein, S. L. and S.A. Moody (2016) “When family history matters: the importance of lineage analyses and fate maps for explaining animal development” Current Topics in Developmental Biology 117: 93-112. (invited for the 50th anniversary volume). PMID: 26969974. Link

Lombard-Banek, C., Moody, S.A., and P. Nemes (2016) Single-cell mass spectrometry for discovery proteomics: quantifying translational cell heterogeneity in the 16-cell frog (Xenopus) embryo. Angewandte Chemie International Edition 55: 2454-2458. PMID: 26756663 Link

Karpinski, B.A., Bryan, C., Paronett, E., Baker, J., Fernandez, A., Horvath, A., Maynard, T.M., Moody, S.A., and A.-S. LaMantia (2016) A cellular and molecular mosaic establishes growth and differentiation states for cranial sensory neurons. Developmental Biology 415: 228-241. PMID: 26988119 Link

Onjiko, R., Morris, S., Moody, S.A. and P. Nemes (2016) Single-cell mass spectrometry with multi-solvent extraction identified metabolic differences between left and right blastomeres in the 8-cell frog (Xenopus) embryo. Analyst 141: 3648-3656. PMID: 27004603 Link

Gaur, S., Mandelbaum, M., Herold, M., Majumdar, H.D., Neilson, K.M., Maynard, T.M., Mood, K., Daar, I.O. and S.A. Moody (2016) Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm. genesis, The Journal of Genetics and Development 54: 334-349. PMID: 27092474 Link

Lombard-Banek, C., Reddi, S., Moody, S.A., and P. Nemes (2016) Label-free quantification of proteins in single embryonic cells by capillary electrophoresis high-resolution mass spectrometry. Molec. Cell. Proteomics Jun 17. pii: mcp.M115.057760. [Epub ahead of print]. PMID: 27317400 Link

Lombard-Banek, C., Moody, S.A. and P. Nemes (2016) “High-sensitivity mass spectrometry for probing gene translation in single embryonic cells in the early frog (Xenopus) embryo. Frontiers in Cell and Developmental Biology, 4:100. doi: 10.3389/fcell.2016.00100. PMID: 27761436.

LaMantia, A.-S., Moody, S.A., Maynard, T., Karpinski, B.A., Zohn, I., Mendelowitz, D., Lee, N.H. and A. Popratiloff (2015) “Hard to swallow: Developmental biological insights into pediatric dysphagia” Developmental Biology, 409: 329-342. PMID: 26554723. Link

Moody, S.A. and S.L. Klein (2015) “Cell lineage tracing for understanding embryonic development” Current Topics in Developmental Biology (invited for the 50th anniversary volume titled: "Essays on Developmental Biology-2016", in preparation).

Moody, S.A., Neilson, K.M., Kenyon, K.L., Alfandari, D., and F. Pignoni (2015) “Using Xenopus to discover new genes involved in Branchiootorenal spectrum disorders” Comparative Biochemistry and Physiology. Part C. (http://dx.doi.org/10.1016/j.cbpc.2015.06.007).

Moody, S.A. and A.-S. LaMantia (2015) “Transcriptional regulation of cranial sensory placode development” Current Topics in Developmental Biology 111: 301-350. PMID: 25662264. Link

Onjiko, R.M., Moody, S.A., and P. Nemes (2015) Single-cell mass spectrometry reveals small molecules that affect cell fates in the 16-cell embryo. Proceedings of the National Academy of Sciences (USA) 112: 6545-6550. PMID: 25941375. Highlighted in Science Signaling; Recommended in F1000Prime Link

Klein, S.L. and S.A. Moody (2015) Early neural ectodermal genes are activated by Siamois and Twin during blastula stages. genesis, The Journal of Genetics and Development 53: 308-320. PMID: 25892704 Link

Yan, B., Neilson, K.M., Ranganathan, R., Streit, A., and S.A. Moody (2015) Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite and kidney development. Developmental Dynamics 244: 181-210. PMID: 25403746 Link

Moody, S.A. and A.-S. LaMantia (2015) “Transcriptional regulation of cranial sensory placode development” Current Topics in Developmental Biology 111: 301-350. PMID: 25662264. Link

Moody, S.A. and Saint-Jeannet, J.-P. (2014) “Determination of pre-placodal ectoderm and sensory placodes.” Developmental Biology (under review)

Saint-Jeannet, J.-P. and S.A. Moody (2014) “Establishing the pre-placodal region and breaking it into placodes with distinct identities” Developmental Biology 389: 13-27. PMCID: PMC3985045. Link

Lee, H.-K., Lee, H.-S. and S.A. Moody (2014) “Neural transcription factors: from embryos to neural stem cells” Molecules and Cells 37: 705-712. PMCID: PMC4213760. Link

Moody, S.A. and Saint-Jeannet, J.-P. (2014) “Determination of pre-placodal ectoderm and sensory placodes.” Developmental Biology (under review)

Grant, P.A., Herold, M.B., and Moody, S.A. (2013) “Blastomere explants to test for cell fate commitment during embryonic development.” Journal of Visualized Experiments (71)e4458, doi: 10.3791/4458 Link

Moody, S.A., Klein S.L., Karpinksi B.A., Maynard T.M. and LaMantia, A.-S. (2013) “On becoming neural: what the embryo can tell us about differentiating neural stem cells.” Amer. J. Stem Cells 2: 74-94. Link

Klein, S.L., Neilson, K.M., Orban, J. Yaklichkin, S., Hoffbauer, J., Mood, K., Daar, I.O. and Moody, S.A. (2013) “Conserved structural domains in FoxD4L1, a neural forkhead box transcription factor, are required to repress or activate target genes.” Plos One Link